EEn should restock by 05/05/2024, ideally. EC by 19/05/2024.

AN IMMEDIATE RECALL OF ALL TRANSDERMAL GEL PURCHASED SINCE THE END OF AUGUST IS IN EFFECT. YOU ARE ADVISED TO DISCONTINUE USE. IF YOU WERE AFFECTED, YOU WILL HAVE BEEN CONTACTED BY THE EMAIL YOU USED TO PURCHASE FROM US. VIEW OUR INCIDENT REPORT HERE.

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Estradiol Gel (110ml)

Transdermal Estradiol Gel is the ideal method of administration for those scared of or unable to access syringes, or for those travelling abroad. Gel comes in  55ml or 110ml airless pump bottles at a concentration of 10mg/ml. The airless pump bottles dispense 0.2ml (2mg) per pump.

Typical locations of administration (in ascending order of absorption) include: forearm, lower stomach, thigh, buttock, armpit, scrotum

Administration to scrotum provides the best absorption, but is associated with pain, likely due to TRPV1. Scrotal administration is not tolerated in all individuals and should be performed with caution. A smaller region of administration is associated with improved absorption. Scrotal absorption will lead to greater variability in estradiol levels.

Do not don clothes until fully dried. Do not bathe for two hours following administration. Caution should be exercised if applying to thin areas of skin such as the face that are susceptible to the drying, damaging, and defatting effects of high concentration alcohol.

If you have small pets, ensure that they do not rub up against areas where you apply the gel, or up against clothes that may rub against such sites and accumulate residues.

Additionally, if being applied by a partner who does not wish to experience feminising effects (or one who is on hormonal birth control; or someone undergoing menopause with intact uterine tissue), please ensure that their hands are washed immediately after applying. Estradiol causes feminisation, can hamper the efficacy of hormonal birth control, and when not paired with a progestin can lead to endometrial cancer in post menopausal individuals.

Store in a cool, dry place, out of direct sunlight. Not suitable for refrigeration.

Out of stock

Additional information

Ingredients

17-B Estradiol (550mg), Isopropyl Alcohol 99% (65.3%), Purified Water (22.2%), Glycerol (5.5%), Isopropyl Myristate (4.7%), Hydroxypropyl methylcellulose (2.2%), Dyes: Rhodamine, Tartrazine (Trace %) — All percentages by weight

Concentration

10mg/ml

Dispensation

0.2ml per pump

Dosage

2mg per pump

Total Volume

110ml

Total Active Ingredient

1100mg

% Alcohol

64.6% by weight

Final Notes

Do not apply to areas of irritated or broken skin. If applied to areas where the skin barrier has been broken, discontinue application in that region until healed.

In the case of the pump mechanism sticking, press repeatedly until gel continues to be dispensed. If after multiple (80+) repetitions, mechanism fails to become unstuck, unscrew pump unit and insert long, thin metallic implement into gel. Depress pump platform, then replace pump unit and repeat depression of pump mechanism.

If you have congenital heart issues or a family history of breast cancer, consult a doctor.

Anecdotal observation suggests that severe connective tissue disorders are more common in trans individuals. If you are hypermobile with a history of joint pain, subluxation, dislocations, or unexplained weakness of cardiac valves, please consider the following:
https://www.ehlers-danlos.com/eds-types/
https://www.nhs.uk/conditions/marfan-syndrome/diagnosis/
https://www.hopkinsmedicine.org/health/conditions-and-diseases/loeysdietz-syndrome
https://www.nhs.uk/conditions/joint-hypermobility-syndrome/

1 review for Estradiol Gel (110ml)

  1. L. M

    convenient and effective, great product

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If injecting, please utilise the following resources prior to injection! If in doubt, ask a nurse at your local hospital. They will show you.

Find injection materials here, or from your local hospital / general practice.